Generic Name: atorvastatin calcium, dosage Form: tablet, film coated, medically reviewed on November 1, 2017, show On This Page. View All, indications and difference between lipitor and zocor Usage for Lipitor, therapy with lipid-altering agents should lipitor dose be only one component of lipitor dose difference between lipitor and zocor multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease difference between lipitor and zocor due to hypercholesterolemia. Drug therapy is recommended as an adjunct to diet when the response to a diet restricted in saturated fat and cholesterol and other nonpharmacologic measures alone has been inadequate. In patients with CHD or multiple risk factors for CHD, Lipitor can be started simultaneously with diet. Prevention of Cardiovascular Disease in Adults. In adult patients without clinically evident coronary heart disease, but with multiple risk factors for coronary heart disease such as age, smoking, hypertension, low HDL-C, or a family history of early coronary heart disease, Lipitor is indicated to: Reduce the risk of myocardial infarction. Reduce the risk of stroke, reduce the risk for revascularization procedures and angina. In adult patients with type 2 diabetes, and without clinically evident coronary heart disease, but with multiple risk factors for coronary heart disease such as retinopathy, albuminuria, smoking, or hypertension, Lipitor is indicated to: Reduce the risk of myocardial infarction. Reduce the risk of stroke, in adult patients with clinically evident coronary heart disease, Lipitor is indicated to: Reduce the risk of non-fatal myocardial infarction. Reduce the risk of fatal and non-fatal stroke. Reduce the risk for revascularization procedures. Reduce the risk of hospitalization for CHF. Reduce the risk of angina, hyperlipidemia, lipitor is indicated: As an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels and to increase HDL-C in adult patients with primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Fredrickson Types IIa and. LDL-C remains 160 mg/dL and: there is a positive family history of premature cardiovascular disease or two or more other CVD risk factors are present in the pediatric patient. Limitations of Use, lipitor has not been studied in conditions where the major lipoprotein abnormality is elevation of chylomicrons (Fredrickson Types I and V). Lipitor Dosage and Administration, hyperlipidemia and Mixed Dyslipidemia. The lipitor dose recommended starting lipitor dose dose of Lipitor is 10 or 20 mg once daily. Patients who require a large reduction in LDL-C (more than 45) may be started at 40 mg once daily. The dosage range of Lipitor is 10 to 80 mg once daily. Lipitor can be administered as a single dose at any time of the day, with or without food. The starting dose and maintenance doses of Lipitor should be individualized according to patient characteristics such as goal of therapy and response. After initiation and/or upon titration of Lipitor, lipid levels should be analyzed within 2 to 4 weeks and dosage adjusted accordingly. Heterozygous Familial Hypercholesterolemia in Pediatric Patients (10 Years to17 Years of Age). The recommended starting dose of Lipitor is 10 mg/day; the usual dose range is 10 to 20 mg orally once daily see. Doses should be individualized according to the recommended goal of therapy see. Indications and Usage (1.2) and, clinical Pharmacology (12). Adjustments should be made at intervals of 4 weeks or more. Homozygous Familial Hypercholesterolemia, the dosage of Lipitor in patients with HoFH is 10 to 80 mg daily. Lipitor should be used as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) in these patients or if such treatments are unavailable. Concomitant Lipid-Lowering Therapy Lipitor may be used with bile acid resins. The combination of HMG-CoA reductase inhibitors difference between lipitor and zocor (statins) and fibrates should generally be used with caution see lipitor dose Warnings and Precautions (5.1) and Drug Interactions (7). Dosage in Patients with Renal Impairment Renal disease does not affect the plasma concentrations nor LDL-C reduction of Lipitor; thus, dosage adjustment in patients with renal dysfunction is not necessary see Warnings and Precautions (5.1) and Clinical Pharmacology (12.3). Dosage in Patients Taking lipitor dose Cyclosporine, Clarithromycin, Itraconazole, or Certain Protease Inhibitors In patients taking cyclosporine or the HIV protease inhibitors (tipranavir plus ritonavir) or the hepatitis C protease inhibitor (telaprevir therapy with Lipitor should be avoided. In patients with HIV taking lopinavir plus ritonavir, caution should be used when prescribing Lipitor and the lowest dose necessary employed. In patients taking clarithromycin, itraconazole, or in patients with HIV taking a combination of saquinavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, or fosamprenavir plus ritonavir, therapy with Lipitor should be limited to 20 mg, and appropriate clinical assessment is recommended to ensure that the lowest. In patients taking the HIV protease inhibitor nelfinavir or the hepatitis C protease inhibitor boceprevir, therapy with Lipitor should be limited to 40 mg, and appropriate clinical assessment is recommended to ensure that the lowest dose necessary of Lipitor is employed see Warnings and Precautions. Dosage Forms and Strengths Lipitor tablets are white elliptical, film-coated, and are available in four strengths (see Table 1 ). Table 1: Lipitor Tablet Strengths and Identifying Features lipitor dose Tablet Strength Identifying Features 10 mg of atorvastatin "PD 155" on one side difference between lipitor and zocor and "10" on the other 20 mg of atorvastatin "PD 156" on one side and "20" on the other. 40 mg of atorvastatin "PD 157" on one side and "40" on the other 80 mg of atorvastatin "PD 158" on one side and "80" on the other Contraindications Warnings and Precautions Skeletal Muscle Rare cases of rhabdomyolysis with acute renal failure secondary to myoglobinuria. A history of renal impairment may be a risk factor for the development of rhabdomyolysis. Such patients merit closer monitoring for skeletal muscle effects. Atorvastatin, like other statins, occasionally causes myopathy, defined as muscle aches or muscle weakness in conjunction with increases in creatine phosphokinase (CPK) values 10 times ULN. The concomitant use of higher doses of atorvastatin with certain drugs such as cyclosporine and strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole, and HIV protease inhibitors) increases the risk of myopathy/rhabdomyolysis. There have been rare reports of immune-mediated necrotizing myopathy (imnm an autoimmune myopathy, associated with statin use.

Cholesterol medication lipitor

Generic Name: atorvastatin (a TOR va sta tin brand Names: Lipitor, medically reviewed on August 2, 2017. Lipitor (atorvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or cholesterol medication lipitor "statins." Atorvastatin reduces levels cholesterol medication lipitor of "bad" cholesterol (low-density cholesterol medication lipitor lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL). Lipitor is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors. Lipitor is for use in adults and children who are at least 10 years old. You should not take Lipitor if you are pregnant or breast-feeding, or if you have liver disease. Stop taking Lipitor and tell your doctor right away if you become pregnant. Serious drug interactions can occur when certain medicines are used together with Lipitor. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using. In rare cases, atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Avoid eating foods that are high in fat or cholesterol. Lipitor will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. Lipitor is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. Before taking this medicine, you should not use Lipitor if you are allergic to atorvastatin, or if you have: liver disease; or if you are pregnant or breast-feeding. Atorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine. Atorvastatin may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking Lipitor. To make sure this medicine is safe for you, tell your doctor if you have ever had: liver problems; muscle pain or weakness; kidney disease; diabetes; a thyroid disorder; or if you drink more than 2 alcoholic beverages daily. Lipitor can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid). Atorvastatin is not approved for use by anyone younger than 10 years old. How should I take Lipitor? Take Lipitor exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended. Lipitor is usually taken once a day, with or without food. Take the medicine at the same time each day. Do not break an Lipitor tablet before taking. You may need to stop using this medicine for a short time if you have: uncontrolled seizures; an electrolyte imbalance (such as high or low potassium levels in your blood severely low blood pressure; a severe infection or illness; or surgery or a medical emergency.

Lipitor is used for

Generic Name: atorvastatin (a TOR va sta tin brand Names: Lipitor, medically reviewed on August 2, 2017. Lipitor (atorvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins." Atorvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the lipitor is used for blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL). Lipitor is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors. Lipitor is for use in adults and children who are at least 10 years old. You should not take Lipitor if you are pregnant or breast-feeding, or if you have liver disease. Stop taking Lipitor and tell your doctor right away if you become pregnant. Serious drug interactions can occur when certain medicines are used together with Lipitor. Tell each of your healthcare providers about lipitor is used for all medicines you use now, and any medicine you start or stop using. In rare cases, atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Avoid eating foods that are high in fat or cholesterol. Lipitor will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. Lipitor is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. Before taking this medicine, you should not use Lipitor if you are allergic to atorvastatin, or if you have: liver disease; or if you are pregnant or breast-feeding. Atorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine. Atorvastatin may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking Lipitor. To make sure this medicine is safe for you, tell your doctor if you have ever had: liver problems; muscle pain or weakness; kidney disease; diabetes; a thyroid disorder; or if you drink more than 2 alcoholic beverages daily. Lipitor can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid). Atorvastatin is not approved for use by anyone younger than 10 years old. How should I take Lipitor? Take Lipitor exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended. Lipitor is usually taken once a day, with or without food. Take the medicine at the same time each day. Do not break an Lipitor tablet before taking. You may need to stop using this medicine for a short time if you have: uncontrolled seizures; an electrolyte imbalance (such as high or low potassium levels in your blood severely low blood pressure; a severe infection or illness; or surgery or a medical emergency. It may take up to 2 weeks before your cholesterol levels improve, and you may need frequent blood test. You may not notice any change in your symptoms, but keep using the medication as directed. Your blood work will help your doctor determine how long to treat you with Lipitor. Lipitor is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely. Store at room temperature away from moisture, heat, and light. Lipitor dosing information Usual Adult Dose for Prevention of Cardiovascular Disease: Initial dose: 10 mg to 80 mg orally once a day. The initial dosage of Lipitor recommended for this patient in the prevention of cardiovascular disease is 10 mg to 80 mg orally once a day. This medicine may be administered at any time of the day without regard for meals. Dose adjustments should be made at intervals of 2 to 4 weeks. Studies have demonstrated that treatment with atorvastatin is associated lipitor is used for with significant reductions in the risk of cardiovascular endpoints and stroke in various patient populations for both primary and secondary prevention. For primary prevention, atorvastatin treatment was effective in hypertensive patients with normal or mildly elevated cholesterol levels as well as in patients with type II diabetes. Patients had relatively low cholesterol levels at baseline in both trials; however, treatment with atorvastatin still resulted in significant reductions in cardiovascular outcomes and stroke. For secondary prevention, intensive lipid lowering therapy with atorvastatin 80 mg/day was associated with significant incremental clinical benefit beyond therapy with 10 mg/day in patients with stable coronary heart disease. It was also shown to significantly reduce the risk of clinical outcomes in coronary heart disease patients versus usual medical care. Usual Adult Dose of Lipitor for Hyperlipidemia: Initial dose: 10, 20 or 40 mg orally once a day. The 40 mg starting dose is recommended for patients who require a reduction in LDL-cholesterol of more than.

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